2.2 Animal tissues, organs and organ systems

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Question 10

Medium

A clinical study compared two methods of replacing a damaged aortic heart valve in elderly patients:

Surgical Aortic Valve Replacement (SAVR) (traditional open-heart surgery)
Transcatheter Aortic Valve Implantation (TAVI) (a minimally invasive keyhole procedure)

The data from the study is shown in the table below:

Measurement	SAVR	TAVI
Number of patients in the study	$3500$	$2500$
Number of patients experiencing major bleeding within 30 days	$224$	$80$
Percentage of patients alive after 3 years	$88%88\%$	$85%85\%$
Percentage of patients requiring a permanent pacemaker within 1 year	$4.0%4.0\%$	$12.0%12.0\%$

Explain why a damaged, leaking heart valve leads to a reduced ability to perform aerobic exercise.

[4]

Give one conclusion comparing the rate of major bleeding within 30 days between the two groups. Include calculations of percentages to support your conclusion.

[3]

Based on the data provided and your biological knowledge, evaluate the choice of TAVI compared to SAVR.

[3]

2.2 Animal tissues, organs and organ systems

Question 10

2.2 Animal tissues, organs and organ systems Questions

2.2 Animal tissues, organs and organ systems

Question 10

2.2 Animal tissues, organs and organ systems Questions