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2.2 Animal tissues, organs and organ systems

2.2 Animal tissues, organs and organ systems

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Question 6

A clinical study compared two methods of replacing a damaged aortic heart valve in elderly patients:

  • Surgical Aortic Valve Replacement (SAVR) (traditional open-heart surgery)
  • Transcatheter Aortic Valve Implantation (TAVI) (a minimally invasive keyhole procedure)

The data from the study is shown in the table below:

MeasurementSAVRTAVI
Number of patients in the study350035003500250025002500
Number of patients experiencing major bleeding within 30 days224224224808080
Percentage of patients alive after 3 years88%88\%88%85%85\%85%
Percentage of patients requiring a permanent pacemaker within 1 year4.0%4.0\%4.0%12.0%12.0\%12.0%
a.

Explain why a damaged, leaking heart valve leads to a reduced ability to perform aerobic exercise.

[4]
b.

Give one conclusion comparing the rate of major bleeding within 30 days between the two groups. Include calculations of percentages to support your conclusion.

[3]
c.

Based on the data provided and your biological knowledge, evaluate the choice of TAVI compared to SAVR.

[3]
Markscheme

2.2 Animal tissues, organs and organ systems Questions

  1. GCSE
  2. /Biology
  3. /2.2 Animal tissues, organs and organ systems

44 exam-style questions on AQA GCSE Biology 2.2 Animal tissues, organs and organ systems, covering 2.2.1 The human digestive system, 2.2.2 The heart and blood vessels, 2.2.3 Blood, 2.2.4 Coronary heart disease: a non-communicable disease, 2.2.5 Health issues, 2.2.6 The effect of lifestyle on some non-communicable diseases, and 2.2.7 Cancer. Each one has a worked solution and a mark scheme showing where the marks go.

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