Two signaling enzymes, Kinase A and Kinase B, are involved in controlling cell division in glioblastoma (a type of brain cancer) cells. Most glioblastoma cells produce both Kinase A and Kinase B. However, some patients have a genetic mutation that prevents their cancer cells from producing functional Kinase B.
The pathway diagram below shows how cell division is regulated in these cancer cells:
Scientists have developed a targeted drug that inhibits the activity of Kinase A.
Explain why this drug can be used to treat glioblastoma in patients who have the gene mutation that stops their cancer cells from producing Kinase B.
Explain why this drug would not be effective in treating glioblastoma in patients whose cancer cells produce both functional Kinase A and Kinase B.