The rate of an enzyme-controlled reaction decreases above the optimum temperature.
Which statement explains why?
The enzyme molecules have less kinetic energy, so they collide less.
The substrate is used up more quickly, so there are fewer collisions.
The active site changes shape, so the substrate no longer fits.
The enzyme is killed by the heat, so it stops working altogether.
184 exam-style questions on OCR GCSE Biology 1.2 What happens in cells (and what do cells need)?, covering 1.2.1 Structure of DNA, 1.2.2 Nucleotides and complementary bases, 1.2.3 Protein synthesis, 1.2.4 DNA structure and the proteins made, 1.2.5 Investigating enzymatic reactions, and 1.2.6 Mechanism of enzyme action. Each one has a worked solution and a mark scheme showing where the marks go.