A change in a gene changes the order of amino acids in an enzyme. The enzyme no longer works.
Which statement explains why?
The enzyme contains fewer bases, so it cannot bind to its substrate.
The enzyme is made in the nucleus, so it cannot reach its substrate.
The enzyme folds differently, so the active site changes shape.
The enzyme is no longer a polymer, so it cannot catalyse a reaction.
184 exam-style questions on OCR GCSE Biology 1.2 What happens in cells (and what do cells need)?, covering 1.2.1 Structure of DNA, 1.2.2 Nucleotides and complementary bases, 1.2.3 Protein synthesis, 1.2.4 DNA structure and the proteins made, 1.2.5 Investigating enzymatic reactions, and 1.2.6 Mechanism of enzyme action. Each one has a worked solution and a mark scheme showing where the marks go.