A mutation replaces one base in a DNA gene. The order of amino acids in the collagen protein changes. The collagen fibres are weaker, so the tissue they support is weaker.
Which statement explains why?
The base replacement changes every amino acid in collagen, so the protein cannot fold into any fibres.
Collagen is used up while it supports tissue, so fewer fibres remain to support the tissue.
The base replacement removes one amino acid, so the collagen chain is too short to form strong fibres.
Different chemical properties of the new amino acid alter attractions, so collagen folds into fibres that are less strong.
184 exam-style questions on OCR GCSE Biology 1.2 What happens in cells (and what do cells need)?, covering 1.2.1 Structure of DNA, 1.2.2 Nucleotides and complementary bases, 1.2.3 Protein synthesis, 1.2.4 DNA structure and the proteins made, 1.2.5 Investigating enzymatic reactions, and 1.2.6 Mechanism of enzyme action. Each one has a worked solution and a mark scheme showing where the marks go.