A patient is treated with a selective V2 V_2\,V2 receptor antagonist, a drug that prevents antidiuretic hormone (ADH) from binding to its receptors on the basolateral membrane of principal cells in the kidney's collecting duct, as illustrated below.
Which row in the table below correctly describes the immediate physiological consequence of administering this antagonist on the collecting duct's apical membrane, the concentration of the urine, and the volume of the urine produced?
Active aquaporins in apical membrane: increased | Urine concentration: increased | Urine volume: decreased
Active aquaporins in apical membrane: decreased | Urine concentration: increased | Urine volume: decreased
Active aquaporins in apical membrane: increased | Urine concentration: decreased | Urine volume: increased
Active aquaporins in apical membrane: decreased | Urine concentration: decreased | Urine volume: increased