Coumatetralyl is a chemical used as a rodenticide (mouse poison). It prevents the liver from synthesizing active chemical proteins needed for blood clotting.

Explain why coumatetralyl can be used as an effective mouse poison.

Resistance to coumatetralyl is caused by a dominant allele, $M$.

Two resistant mice mate and produce non-resistant offspring.

Draw a genetic diagram (such as a Punnett square) to show how these non-resistant offspring can be produced.

When scientists studied the resistant mice, they found two different genotypes:

• Homozygous resistant mice ($MM$) require extremely high levels of vitamin K in their diet to survive.
• Heterozygous resistant mice ($Mm$) require only normal levels of vitamin K.

Scientists observed that the non-resistant allele ($m$) never disappears completely from the wild population. Explain why.

Name the enzyme used to join two sections of DNA together in genetic engineering.

Scientists believe they can control the mouse population using genetic engineering. They want to insert a gene into male mice that destroys all of their sperm containing a Y chromosome.

Explain how this method of genetic engineering would rapidly reduce the wild mouse population.