In combating global health challenges, monitoring and maintaining patient health increasingly relies on genomic medicine. Which of the following represents an application of genomic medicine to personalize treatment for a patient diagnosed with a chronic disease?
Screening a patient's genome for specific alleles of the CYP2C19\textit{CYP2C19}CYP2C19 gene to determine the optimal dosage of the antiplatelet drug clopidogrel and avoid adverse cardiovascular events.
Using polymerase chain reaction (PCR) to amplify and detect the presence of bacterial DNA in a patient's cerebrospinal fluid to rapidly diagnose bacterial meningitis.
Synthesizing human insulin using genetically modified Escherichia coli\textit{Escherichia coli}Escherichia coli to ensure a reliable global supply of hormone therapy for type 1 diabetics.
Analyzing family medical histories across three generations to calculate the statistical probability of future offspring developing type 2 diabetes.
97 exam-style questions on OCR GCSE Biology 6.3 Monitoring and maintaining health, covering 6.3.1 Health and disease, 6.3.2 Interactions between diseases, 6.3.3 Spread of communicable diseases, 6.3.4 Common infections and diseases, 6.3.5 Physical plant defence responses, 6.3.6 Chemical plant defence responses, 6.3.7 Detecting and identifying plant diseases, 6.3.8 White blood cells and platelets, 6.3.9 Non-specific defence systems, 6.3.10 The immune system, 6.3.11 Monoclonal antibodies, 6.3.12 Vaccines and medicines, 6.3.13 Aseptic techniques, 6.3.14 Discovery and development of new medicines, 6.3.15 Causes of non-communicable diseases, 6.3.16 Treatments for cardiovascular disease, 6.3.17 Lifestyle factors and non-communicable diseases, 6.3.18 Cancer, 6.3.19 Stem cells in medicine, 6.3.20 Gene technology in medicine, and 6.3.21 The human genome and medicine. Each one has a worked solution and a mark scheme showing where the marks go.