An industrial fermenter (bioreactor) is used to cultivate microorganisms under controlled conditions for large-scale production of biological substances.

Explain how the cooling jacket regulates the temperature inside the fermenter.
Explain why it is crucial to keep the temperature near the optimum level for the growing microorganisms.
Explain the purpose of the stirring paddles in the fermenter.
Other than temperature, identify one condition inside the fermenter that must be carefully controlled, and explain the consequence of failing to control it.
Name one specific commercial or medical product manufactured using this type of bioreactor technology.