The Figure shows a Siamese cat.
Figure

The colour of the fur is controlled by a gene that codes for an enzyme. The enzyme makes a dark pigment in the fur.
In Siamese cats, the allele for this enzyme codes for an enzyme that only works at temperatures below 33 ∘C33\ ^{\circ}\text{C}33 ∘C. Above this temperature the enzyme is denatured.
Explain why Siamese cats have dark fur on their ears, face, paws and tail but pale fur on their body.
A vet shaved a patch of fur from the back of a Siamese cat. An ice pack was kept on the shaved patch while the fur grew back.
Predict the colour of the fur that grew back. Explain your answer.
Explain why the fur colour of Siamese cats is an example of both genetic and environmental variation.
Siamese kittens have completely pale fur when they are born.
Suggest why.
40 exam-style questions on Edexcel GCSE Biology 3.4 Variation and the Human Genome Project, covering 3.4.1 Causes of variation, 3.4.2 Outcomes of the Human Genome Project, 3.4.3 Genetic variation within a population, and 3.4.4 Effects of genetic mutations on phenotype. Each one has a worked solution and a mark scheme showing where the marks go.