In people with an inherited disorder, an allele produces an enzyme with reduced activity. A research team determines the three-dimensional shape and function of this enzyme.
How could this information be used in medicine?
To identify carriers by comparing their DNA sequence with a reference genome.
To guide the development of a treatment for the inherited disorder.
To select a medicine or dose using an individual's genomic information.
To estimate disease risk by comparing allele frequencies in different groups.
96 exam-style questions on Edexcel GCSE Biology 3.4 Variation and the Human Genome Project, covering 3.4.1 Causes of variation, 3.4.2 Outcomes of the Human Genome Project, 3.4.3 Genetic variation within a population, and 3.4.4 Effects of genetic mutations on phenotype. Each one has a worked solution and a mark scheme showing where the marks go.