Monitoring and maintaining health

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Question 15
Medium

An epidemiologist is evaluating two clinical interventions to maintain public health during an outbreak of a toxin-producing bacterium:

  • Intervention X: Administration of a toxoid vaccine (an inactivated bacterial toxin).
  • Intervention Y: Administration of pre-formed monoclonal antitoxin antibodies.

Which statement correctly compares the immunological mechanisms and outcomes of these two interventions?

Intervention X provides passive immunity because the toxoid is an inactive antigen, whereas Intervention Y provides active immunity because the monoclonal antibodies actively neutralize the toxin.

Intervention X stimulates the host's B lymphocytes to undergo clonal selection and produce memory cells, offering long-term protection, whereas Intervention Y provides immediate, temporary protection because the injected antibodies do not stimulate the production of memory cells.

Intervention X relies on cytotoxic T lymphocytes to destroy infected host cells directly for immediate protection, whereas Intervention Y depends on the monoclonal antibodies multiplying within the lymphatic system to provide lifelong immunity.

Both interventions induce active immunity, but Intervention X is preferred for immediate outbreak control because the toxoid stimulates faster clonal expansion than pre-formed monoclonal antibodies.

Monitoring and maintaining health Questions

  1. GCSE
  2. /Biology
  3. /Monitoring and maintaining health