A mouse is exposed to antigen X. Its lymphocytes are fused with tumour cells, producing many hybridomas. Only some hybridomas produce antibodies that bind to X.
Which procedure will produce a large supply of identical antibodies against X?
Select all surviving hybridomas, mix them and collect antibodies from their descendants.
Select one original tumour cell, clone it and collect antibodies from its descendants.
Select all original lymphocytes, mix them and collect antigens from their descendants.
Select one suitable hybridoma, clone it and collect antibodies from its descendants.
45 exam-style questions on Edexcel GCSE Biology 5.3 Immune system and medicines, covering 5.3.1 The specific immune system, 5.3.2 Response to immunisation, 5.3.3 Advantages and disadvantages of immunisation, 5.3.4 Antibiotics and bacterial infections, 5.3.5 Aseptic techniques in culturing, 5.3.6 Cross-sectional areas of cultures, 5.3.7 Stages of developing new medicines, and 5.3.8 Production of monoclonal antibodies. Each one has a worked solution and a mark scheme showing where the marks go.