Four tablet formulations of a medicine for reducing joint pain are compared in a clinical trial.
A formulation will continue to be tested if at least 80% of patients report reduced pain and no more than 4% of patients report side effects.
| Formulation | Number of patients | Patients reporting reduced pain | Patients reporting side effects |
|---|---|---|---|
| L | 150 | 126 | 9 |
| M | 200 | 158 | 6 |
| N | 120 | 90 | 6 |
| O | 250 | 205 | 10 |
Which formulation would be rejected only because its side-effect rate is too high?
formulation O
formulation M
formulation N
formulation L
87 exam-style questions on Edexcel GCSE Biology 5.3 Immune system and medicines, covering 5.3.1 The specific immune system, 5.3.2 Response to immunisation, 5.3.3 Advantages and disadvantages of immunisation, 5.3.4 Antibiotics and bacterial infections, 5.3.5 Aseptic techniques in culturing, 5.3.6 Cross-sectional areas of cultures, 5.3.7 Stages of developing new medicines, and 5.3.8 Production of monoclonal antibodies. Each one has a worked solution and a mark scheme showing where the marks go.