A medicine is being tested to reduce symptoms of a skin condition. In a clinical trial, patients were randomly allocated to receive one of two doses. After four weeks, the results were recorded.
| Treatment | Number of patients | Number whose symptoms improved | Number reporting at least one side effect |
|---|---|---|---|
| lower dose | 200 | 126 | 20 |
| higher dose | 200 | 150 | 48 |
Explain which dose should be tested in a larger clinical trial. Use calculations based on the data to support your answer.
87 exam-style questions on Edexcel GCSE Biology 5.3 Immune system and medicines, covering 5.3.1 The specific immune system, 5.3.2 Response to immunisation, 5.3.3 Advantages and disadvantages of immunisation, 5.3.4 Antibiotics and bacterial infections, 5.3.5 Aseptic techniques in culturing, 5.3.6 Cross-sectional areas of cultures, 5.3.7 Stages of developing new medicines, and 5.3.8 Production of monoclonal antibodies. Each one has a worked solution and a mark scheme showing where the marks go.