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Antibiotics, culturing microorganisms and monoclonal antibodies

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Question 18

A clinical trial was conducted to evaluate the efficacy of a newly developed monoclonal antibody (mAb-42) designed to target and neutralize a spike protein on a viral pathogen. Table 1 shows the percentage of viral cultures showing a greater than 90% reduction in viral load across four different dosage levels, compared to a standard antiviral drug control group.

Table 1

Dosage of mAb-42 (mg/kg\text{mg/kg}mg/kg)Cultures showing >90% reduction with mAb-42 (%)Cultures showing >90% reduction with standard control (%)
1.514.812.5
3.032.428.6
6.065.258.1
12.091.584.0

At a dosage of 1.5 mg/kg, 7,815 cultures treated with the monoclonal antibody mAb-42 showed a greater than 90% reduction in viral load.

Calculate the total number of viral cultures treated with mAb-42 at this dosage in this clinical trial.

Give your answer to 4 significant figures.

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Antibiotics, culturing microorganisms and monoclonal antibodies Questions

  1. GCSE
  2. /Biology
  3. /Antibiotics, culturing microorganisms and monoclonal antibodies