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Genetics and evolution

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Question 16

The pedigree diagram below shows the inheritance of a rare genetic disorder in three generations of a family.

Pedigree Diagram

Which of the following statements correctly identifies a possible or impossible mode of inheritance for this disorder, with the correct genetic reasoning?

The condition cannot be X-linked recessive because individual III-3 is an unaffected male whose mother (II-1) is affected.

The condition cannot be autosomal dominant because the affected father (I-1) produced unaffected sons (II-2 and II-4).

The condition must be X-linked dominant because all daughters of the affected male (I-1) are affected, whereas all of his sons are unaffected.

The condition cannot be autosomal recessive because the unaffected male (II-5) and affected female (II-1) have both affected and unaffected children.

Genetics and evolution Questions

  1. A Level
  2. /Biology
  3. /Genetics and evolution