Homeobox genes are regulatory genes critical for directing developmental patterns in eukaryotes, and Hox genes represent a specific group within this gene family.
Which row in the table below correctly identifies the relationship between Hox and homeobox genes, their corresponding nucleotide and polypeptide lengths, the molecular target of the homeodomain, and the typical phenotypic consequence of a loss-of-function mutation?
RelationshipSequence lengthsMolecular TargetMutation EffectAHox genes are a subset of homeobox genes180-bp DNA encodes 60-aa domainSpecific DNA sequencesHomeotic transformationBHox genes are a completely distinct family60-bp DNA encodes 180-aa domainSpecific DNA sequencesArrest of mitotic divisionCHox genes are a subset of homeobox genes180-bp DNA encodes 60-aa domainMessenger RNA moleculesFailure of cell respirationDHox genes are found only in plants and fungi60-bp DNA encodes 180-aa domainRibosomal RNAHomeotic transformation \begin{array}{|c|l|l|l|l|} \hline & \mathbf{Relationship} & \mathbf{Sequence\ lengths} & \mathbf{Molecular\ Target} & \mathbf{Mutation\ Effect} \\ \hline \mathbf{A} & \text{Hox genes are a subset of homeobox genes} & \text{180-bp DNA encodes 60-aa domain} & \text{Specific DNA sequences} & \text{Homeotic transformation} \\ \hline \mathbf{B} & \text{Hox genes are a completely distinct family} & \text{60-bp DNA encodes 180-aa domain} & \text{Specific DNA sequences} & \text{Arrest of mitotic division} \\ \hline \mathbf{C} & \text{Hox genes are a subset of homeobox genes} & \text{180-bp DNA encodes 60-aa domain} & \text{Messenger RNA molecules} & \text{Failure of cell respiration} \\ \hline \mathbf{D} & \text{Hox genes are found only in plants and fungi} & \text{60-bp DNA encodes 180-aa domain} & \text{Ribosomal RNA} & \text{Homeotic transformation} \\ \hline \end{array} ABCDRelationshipHox genes are a subset of homeobox genesHox genes are a completely distinct familyHox genes are a subset of homeobox genesHox genes are found only in plants and fungiSequence lengths180-bp DNA encodes 60-aa domain60-bp DNA encodes 180-aa domain180-bp DNA encodes 60-aa domain60-bp DNA encodes 180-aa domainMolecular TargetSpecific DNA sequencesSpecific DNA sequencesMessenger RNA moleculesRibosomal RNAMutation EffectHomeotic transformationArrest of mitotic divisionFailure of cell respirationHomeotic transformationRow A
Row B
Row C
Row D
