Inheritance

EasyMediumHard
123456789101112131415161718192021222324252627282930313233343536
Question 15
Medium

Huntington's disease is an inherited disorder that affects the brain. It is caused by a dominant allele.

a.

The family tree shows the inheritance of Huntington's disease in a family.

Pedigree diagram showing three generations of a family

Complete the table using the information in the family tree:

  • Number of people who will develop Huntington's disease: 4
  • Number of people who are homozygous recessive for this gene: ___________
  • Number of people who are heterozygous for this gene: ___________
[2]
b.

Person A and Person B are expecting another child. Complete a genetic diagram (using HHH for the dominant allele and hhh for the recessive allele) to find the probability that this child will develop Huntington's disease.

[3]
c.

This type of Huntington’s disease is a genetic disease. Give one reason why genetic diseases are classified as non-communicable.

[1]
d.

Huntington's disease is caused by an abnormal protein produced in the brain. Scientists are working on a treatment using artificial monoclonal antibodies designed to target this specific protein.

Explain why the body does not naturally produce its own antibodies against the abnormal huntingtin protein.

[2]
e.

Suggest two reasons why some people are opposed to testing new medicines on animals.

[2]

Inheritance Questions

  1. GCSE
  2. /Biology
  3. /Inheritance