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Inheritance and genetic crosses

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Question 13

The pedigree chart below shows the inheritance of a rare genetic condition in three generations of a family.

Pedigree diagram

Which of the following correctly explains the evidence from this chart regarding whether the allele for the condition is dominant or recessive, and whether it is sex-linked or autosomal?

The allele is recessive because unaffected parents 5 and 6 have an affected child (7). It is sex-linked because males (7) are much more likely to be affected by recessive conditions than females.

The allele is recessive because unaffected parents 1 and 2 have an affected child (4). It is autosomal because if it were sex-linked recessive, the affected male (7) would have to inherit his affected X chromosome from his father (6), who would therefore also be affected.

The allele is recessive because unaffected parents 1 and 2 have an affected child (4). It is autosomal because if it were sex-linked recessive, the affected female (4) would have to inherit an affected X chromosome from her father (1), who would therefore also be affected.

The allele is dominant because unaffected parents 1 and 2 have an affected child (4). It is autosomal because the condition affects both males and females in equal proportions across the three generations.

Inheritance and genetic crosses Questions

  1. GCSE
  2. /Biology
  3. /Inheritance and genetic crosses