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Mitosis, growth and stem cells

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Question 19

A research group is studying the cell cycle of human embryonic stem cells (hESCs) cultured in vitro for potential applications in regenerative medicine. During their microscopic observations of mitotic cells, they record four distinct cellular events:

  1. Centromeres divide, and sister chromatids are pulled to opposite poles of the cell by shortening spindle fibres.
  2. Chromosomes align along the equator of the cell, with spindle fibres attached to their centromeres.
  3. Chromatin condenses into visible chromosomes, the nucleolus disappears, and the nuclear envelope breaks down.
  4. Chromosomes reach opposite poles of the spindle, decondense, and nuclear envelopes reform.

Which of the following options correctly identifies the chronological sequence of these mitotic events and the potency classification of the cultured hESCs?

Sequence: 3→2→1→43 \rightarrow 2 \rightarrow 1 \rightarrow 43→2→1→4; Potency: Pluripotent

Sequence: 3→1→2→43 \rightarrow 1 \rightarrow 2 \rightarrow 43→1→2→4; Potency: Totipotent

Sequence: 3→2→1→43 \rightarrow 2 \rightarrow 1 \rightarrow 43→2→1→4; Potency: Multipotent

Sequence: 2→3→1→42 \rightarrow 3 \rightarrow 1 \rightarrow 42→3→1→4; Potency: Pluripotent

Mitosis, growth and stem cells Questions

  1. GCSE
  2. /Biology
  3. /Mitosis, growth and stem cells