An experiment was conducted on mammalian skeletal muscle cells to study the metabolic effects of different respiration inhibitors. Table 1.1 shows the production rate of three key respiratory markers: ATP, carbon dioxide (CO2\text{CO}_2CO2), and triose phosphate (TP) in cells treated with antimycin A, 2-deoxyglucose (2-DG), or a control phosphate-buffered saline (PBS) solution containing glucose.
Table 1.1
| Treatment | ATP (10−10 mol s−1)\text{ATP } (10^{-10}\text{ mol s}^{-1})ATP (10−10 mol s−1) | CO2 (10−11 mol s−1)\text{CO}_2\text{ } (10^{-11}\text{ mol s}^{-1})CO2 (10−11 mol s−1) | Triose phosphate (TP) (10−11 mol s−1)\text{Triose phosphate (TP) } (10^{-11}\text{ mol s}^{-1})Triose phosphate (TP) (10−11 mol s−1) |
|---|---|---|---|
| Antimycin A | 1.851.851.85 | 0.000.000.00 | 4.654.654.65 |
| 2-Deoxyglucose (2-DG) | 0.000.000.00 | 0.000.000.00 | 0.000.000.00 |
| Control | 5.805.805.80 | 2.902.902.90 | 4.404.404.40 |
Based on the data in Table 1.1, compare the effects of antimycin A and 2-deoxyglucose (2-DG) on respiration in these cells, and deduce which stage of respiration each inhibitor targets.
