Purity, formulations and chromatography

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Question 1
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This question is about lithium carbonate tablets, which are commonly prescribed as mood-stabilising medications.

Lithium carbonate contains lithium ions (Li+Li^+Li+) and carbonate ions (CO32−CO_3^{2-}CO32−​).

a.

A student wants to test a lithium carbonate tablet to confirm the presence of both lithium ions and carbonate ions. They are provided with:

  • a nichrome wire
  • dilute hydrochloric acid
  • limewater

Plan an investigation to show the presence of lithium ions and carbonate ions in the tablet. You should include the expected results of the tests for both ions.

[5]
b.

Besides the active pharmaceutical ingredient, the tablet contains other substances such as binders, disintegrants, and coatings. These ingredients are present in exact, pre-determined quantities to ensure the tablet dissolves at the correct rate in the body. What chemical term is used to describe mixtures workload as a useful product in this way?

[1]
c.

A single tablet has a total mass of 1.35 g and contains 400 mg of lithium carbonate. Calculate the percentage by mass of lithium carbonate in this tablet. Give your answer to 3 significant figures.

[3]

Purity, formulations and chromatography Questions

  1. GCSE
  2. /Chemistry
  3. /Purity, formulations and chromatography