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5.1.7 Spread and prevention of STIs

STIs Spread Through Sexual Contact or Body Fluids

Definition

Sexually transmitted infection

An infection spread from person to person through sexual contact or the exchange of body fluids.

  1. A sexually transmitted infection is an infection passed mainly through sexual contact or exchange of infected body fluids.
  2. An infected person may have no symptoms and can still transmit the pathogen.
Key Idea

Prevention reduces contact with infected fluids, identifies infections early and treats them where treatment is available.

Chlamydia Is a Bacterial STI

  1. Chlamydia is caused by bacteria and is transmitted during unprotected sexual contact.
  2. It often causes no symptoms, but it may cause pain when urinating or unusual discharge.
  3. Untreated infection can spread through the reproductive system and cause pelvic inflammatory disease and infertility.
  4. Barrier contraception reduces transmission, while testing and antibiotics identify and treat infected people and their partners.
  5. Chlamydia infects cells lining the reproductive tract and may spread to the uterus and oviducts, where inflammation and scarring can block an oviduct.
Example

testing matters because a person without symptoms can receive antibiotics before unknowingly passing chlamydia to a partner.

HIV Damages Immune Defence

Definition

HIV

Human immunodeficiency virus: a virus that infects and destroys white blood cells, weakening the immune system. If untreated it can lead to AIDS.

Definition

AIDS

Acquired immune deficiency syndrome: the late stage of HIV infection, when the immune system is so badly damaged that the body can no longer fight off other infections and cancers.

  1. HIV is present in blood, semen, vaginal fluids and breast milk.
  2. It can spread through unprotected sex, shared needles, infected blood, and from mother to baby during pregnancy, birth or breastfeeding.
  3. HIV infects and destroys white blood cells, weakening the immune system.
  4. AIDS is the late stage of untreated HIV infection, when severe immune damage allows opportunistic infections and some cancers to develop.
  5. HIV transmission requires infected fluid to reach another person's bloodstream or vulnerable tissue.

Routes of HIV transmission through sexual contact, shared needles, infected blood and transmission from mother to baby.

Common Mistake

HIV is the virus, while AIDS is the condition that can develop after long-term immune-system damage.

Several Measures Reduce HIV Transmission

Definition

Antiretroviral drug

A medicine that controls HIV by stopping the virus reproducing, slowing or preventing the onset of AIDS.

  1. Condoms reduce exchange of infected sexual fluids.
  2. Sterile needles prevent transfer of infected blood.
  3. Screening donated blood prevents infected blood products being used.
  4. Testing allows infected people to begin treatment and take steps to avoid transmission.
  5. Antiretroviral drugs reduce viral replication, protecting white blood cells and lowering the amount of virus in the blood.
  6. Treatment during pregnancy and birth greatly reduces transmission from mother to baby.
  7. Antiretroviral therapy uses combinations of drugs to inhibit stages of viral replication, reducing viral load and protecting white blood cells.
  8. A lower viral load reduces transmission risk, but treatment does not remove the virus from the body.
  9. Condoms reduce exchange of sexual fluids, sterile needles prevent blood-to-blood transfer and screened donations prevent infected transfusions.
Exam technique
  • Link each measure to the route it blocks: condoms block sexual-fluid exchange, sterile needles block blood-to-blood transfer, and screening blocks infected transfusions.
  • Do not state that antibiotics treat HIV because antibiotics act on bacteria, not viruses.

Prevention Does Not Depend on Symptoms

  1. Regular testing is necessary because chlamydia and early HIV infection may be asymptomatic.
  2. Partner notification allows exposed people to be tested and treated.
  3. A person with asymptomatic chlamydia can transmit bacteria without knowing, which is why screening and partner notification are needed.
Self review
  • How is chlamydia transmitted and treated?
  • Why can untreated chlamydia cause infertility?
  • Give three routes of HIV transmission.
  • How do antiretroviral drugs reduce HIV transmission?
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A sexually transmitted infection, or STI, is an infection passed mainly through sexual contact or the exchange of infected body fluids. Each STI is caused by a pathogen, such as a bacterium or virus.

An infected person may have no symptoms but can still transmit the pathogen. Prevention therefore includes reducing contact with infected fluids, testing people who may be infected, and providing suitable treatment.

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Chlamydia is caused by [     ].

5.1.7 Spread and prevention of STIs Revision Guide

  1. GCSE
  2. /Biology
  3. /5.1.7 Spread and prevention of STIs

Revision notes for Edexcel GCSE Biology 5.1.7 Spread and prevention of STIs: explanations and worked examples.

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