During an investigation, a laboratory animal is given an injection of TSH into its bloodstream. Its hypothalamus, pituitary gland and thyroid gland are functioning normally. The release of TRH and thyroxine is then monitored.
Which sequence is most likely while the injected TSH is having an effect?
The TSH inhibits the thyroid gland, reducing thyroxine release and therefore increasing TRH release.
The TSH inhibits the hypothalamus, reducing TRH release and therefore reducing thyroxine release.
The TSH stimulates the thyroid gland to release more thyroxine, which increases TRH release.
The TSH stimulates the thyroid gland to release more thyroxine, which reduces TRH release.
89 exam-style questions on Edexcel GCSE Biology 7.1 Hormones and coordination, covering 7.1.1 Endocrine glands and hormone transport, 7.1.2 Adrenalin and fight or flight, and 7.1.3 Thyroxine and negative feedback. Each one has a worked solution and a mark scheme showing where the marks go.