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3.3.4 Determination of sex at fertilisation

Sex chromosomes

Definition

Sex chromosomes

The pair of chromosomes that determine biological sex: XX in females and XY in males.

  1. One of the 232323 pairs of chromosomes is the pair of sex chromosomes.
  2. Females have two X chromosomes (XXXXXX).
  3. Males have one X and one Y chromosome (XYXYXY).
  4. The other 222222 pairs are the same type in both sexes.
Note

The Y chromosome carries the genes that lead to male development.

Hint

Females are XXXXXX and males are XYXYXY: the male has the Y.

How sex is determined

Definition

Punnett square

A grid used to predict the possible genotypes and phenotypes of offspring from a genetic cross.

  1. All egg cells carry one X chromosome.
  2. Half the sperm carry an X and half carry a Y.
  3. If an X sperm fertilises the egg, the child is XXXXXX (female).
  4. If a Y sperm fertilises the egg, the child is XYXYXY (male).
  5. So there is a 1:11:11:1 ratio, giving about a 50%50\%50% chance of each sex.
Example

Worked cross: determining sex

  • Parental sex chromosomes: mother XXXXXX and father XYXYXY.
  • Gametes: every egg carries XXX; half the sperm carry XXX and half carry YYY.
  • Possible offspring: XXXXXX, XXXXXX, XYXYXY and XYXYXY.
  • Outcome: 222 female : 222 male, which simplifies to a 1:11:11:1 ratio.
  • Probability: each fertilisation has a 12\dfrac{1}{2}21​ or 50%50\%50% chance of producing an XXXXXX offspring and the same chance of producing an XYXYXY offspring.
Common Mistake

Do not say the mother decides the sex: the sperm carries the X or Y that decides it.

A Punnett square showing sex determination in humans. The mother's gametes (X, X) are across the top and the father's gametes (X, Y) are down the side. The resulting offspring genotypes are 50% XX (female) and 50% XY (male).

Self review
  • Which sex chromosomes do females and males have?
  • Which parent's gamete decides the sex of the child?
  • What is the ratio of male to female offspring?
  • What is the chance that a child is male?
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Humans have 232323 pairs of chromosomes in most body cells. One pair consists of the sex chromosomes, while the other 222222 pairs are autosomes.

A female usually has two X chromosomes, written XXXXXX. A male usually has one X chromosome and one Y chromosome, written XYXYXY.

The Y chromosome carries genes that usually lead to male development. Therefore, the presence of a Y chromosome is the key difference between the two combinations.

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Which sex chromosomes does a female have?

3.3.4 Determination of sex at fertilisation Revision Guide

  1. GCSE
  2. /Biology
  3. /3.3.4 Determination of sex at fertilisation

Revision notes for Edexcel GCSE Biology 3.3.4 Determination of sex at fertilisation: explanations and worked examples.

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