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5.2.2 The brain (biology only)

5.2.2 The brain (biology only)

5.2.2a The brain

The Brain Is Billions of Neurones Controlling Complex Behaviour

  1. The brain is part of the central nervous system and controls complex behaviour.
  2. It is made of billions of interconnected neurones.
  3. It has different regions that each carry out different functions.
Key Idea

Because different regions of the brain control different functions, damage to one region affects one particular function.

The Cerebral Cortex: Consciousness, Memory and Language

Definition

Cerebral cortex

The highly folded outer layer of the brain, responsible for consciousness, intelligence, memory and language.

  1. The cerebral cortex is the highly folded outer layer of the brain.
  2. It is concerned with consciousness, intelligence, memory and language.
Note

The brain is separate (triple) science biology only.

The Cerebellum: Muscle Coordination and Balance

Definition

Cerebellum

The region at the back of the brain that coordinates muscular activity, movement and balance.

  1. The cerebellum sits at the back of the brain, underneath the cerebral cortex.
  2. It coordinates muscular activity, movement and balance.
Example

Riding a bike smoothly, balancing and catching a ball all rely on the cerebellum coordinating your muscles.

A diagram showing the location of the cerebellum in the brain and its functions, including receiving sensory input for body position, coordinating muscle performance based on motor instructions, and managing balance.

The Medulla: Unconscious Vital Functions

Definition

Medulla

The region of the brain that controls unconscious activities such as heart rate and breathing.

  1. The medulla controls unconscious activities such as heart rate and breathing.
  2. You do not have to think about these actions, which is why the medulla is vital for staying alive.
  3. Other regions have their own jobs too: the hypothalamus helps control body temperature and the pituitary gland releases hormones, both covered in other topics.

A diagram of the brain highlighting the medulla oblongata, listing its functions as the control center for heart rate, breathing, and blood pressure, and its role in processing sensory input from baroreceptors and chemoreceptors.

A diagram showing the location of the hypothalamus in the brain and its connection to the pituitary gland, listing its roles in homeostasis, hormone production, and regulating body functions like sleep and appetite.

Self review
  • What is the brain made of, and what does it control?
  • Where is the cerebral cortex and what functions does it control?
  • What does the cerebellum do?
  • Name two activities controlled by the medulla.

5.2.2b The brain (Higher tier)

Mapping the Brain Is Hard but Possible

  1. The brain is extremely complex and delicate, and its regions cannot easily be studied in isolation.
  2. Even so, neuroscientists have mapped many regions to their functions using three main approaches.
Note

This topic is Higher tier and separate (triple) biology only.

Studying Patients With Brain Damage

  1. When part of the brain is damaged, scientists can match the change in behaviour or ability to the damaged region.
  2. This links a particular region to a particular function.
Example

Phineas Gage survived an iron rod passing through part of his cerebral cortex, but his personality changed drastically, which helped map that region to social behaviour.

Electrically Stimulating the Brain

  1. Tiny electrodes can be used to give a small electrical stimulation to a region of the brain.
  2. The effect is observed, such as a movement or a feeling of hunger or fear, which reveals what that region does.
Note

There are no pain receptors in the brain itself, so this can be done while a patient is conscious.

MRI Scanning

Definition

MRI scan

A magnetic resonance imaging scan that produces detailed images of the brain in a living person, showing which regions are active or damaged.

  1. An MRI scan uses magnetic fields to produce detailed images of the brain in a living person.
  2. It can show a damaged area, such as a tumour or the effects of a stroke.
  3. A functional MRI shows which regions are active during a task by detecting the increased blood flow to those regions.
Key Idea

MRI lets scientists watch a living brain at work without opening the skull, which is why it has transformed brain research.

Why Treating the Brain Is So Difficult

  1. The brain's complexity and delicacy make it very easy to damage and hard to repair.
  2. Drugs may not reach the brain because of the membranes surrounding it, and surgery is risky because it is not fully understood what every area does.
  3. Accidental damage can cause permanent problems with speech, movement or personality.
  4. When you evaluate a procedure, weigh the benefit (treating a disorder and improving quality of life) against the risk (permanent damage, made worse by our incomplete understanding).
Self review
  • Give two reasons the brain is difficult to study and treat.
  • How can studying patients with brain damage help map brain functions?
  • What can be learned by electrically stimulating the brain, and why can it be done on a conscious patient?
  • What is an MRI scan, and what does a functional MRI show?
  • Give one benefit and one risk of carrying out a procedure on the brain.
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Side-view brain diagram showing the cerebral cortex, cerebellum and medulla with their functions

The brain is part of the central nervous system. It is made of billions of interconnected neurones and controls complex behaviour.

Different regions carry out different functions. Damage to one region can therefore affect a particular function rather than all brain activity.

The cerebral cortex is the highly folded outer layer and is involved in consciousness, intelligence, memory and language. The cerebellum coordinates muscular activity, movement and balance, while the medulla controls unconscious functions such as heart rate and breathing.

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5.2.2 The brain Revision Guide

  1. GCSE
  2. /Biology
  3. /5.2.2 The brain

Revision notes for AQA GCSE Biology 5.2.2 The brain. Open the guide for explanations and worked examples. Written against the AQA GCSE Biology (8461) specification, so the content matches what's examinable rather than general Biology background.