3.1 Communicable diseases

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Question 1
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A patient receives a primary vaccine dose at day 0 and a booster dose at day 30. The graph below shows the changes in the antibody concentration of their blood over a 50-day period.

A line graph plotting antibody concentration in arbitrary units (AU) on the y-axis against time in days on the x-axis. The y-axis goes from 0 to 200 AU. The x-axis goes from 0 to 50 days. At day 0 (indicated by an arrow labeled 'Primary dose'), the antibody concentration is 0 AU. The curve rises to a first peak of 20 AU at day 10, then decreases to 5 AU at day 30 (indicated by a second arrow labeled 'Booster dose'). After day 30, the curve rises extremely sharply to a second, much higher peak of 180 AU at day 35, before starting to decline slowly.

Using the data from the graph:

a.

Calculate the percentage increase in peak antibody concentration from the first peak to the second peak.

[2]
b.

Calculate and compare the mean rate of increase in antibody concentration (in AU/day\text{AU}/\text{day}AU/day) from the time of injection to the peak concentration for both:

  • the primary dose (from day 0 to day 10)
  • the booster dose (from day 30 to day 35)
[3]

3.1 Communicable diseases Questions

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