Nucleotides and nucleic acids

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Question 3
Medium

The diagram below shows a section of a replicating DNA molecule, featuring a template strand on the left and a newly synthesized strand on the right with an incoming nucleotide.

DNA Replication Fork Diagram

Which of the following statements correctly describes the molecular structure and replication process shown in the diagram?

DNA polymerase catalyzes the formation of Bond 2 between complementary bases, while Bond 1 is formed spontaneously without enzyme action.

DNA polymerase catalyzes a condensation reaction at End Z, forming a covalent phosphodiester bond (Bond 1) between the 3′-OH3'\text{-OH}3′-OH group and the 5′5'5′ phosphate of the incoming nucleotide.

End Y represents the 3′3'3′ end of the newly synthesized strand, meaning that replication proceeds in the 3′3'3′ to 5′5'5′ direction.

Bond 1 represents a hydrogen bond within the sugar-phosphate backbone, while Bond 2 is a covalent phosphodiester bond between complementary base pairs.

Nucleotides and nucleic acids Questions

  1. A Level
  2. /Biology
  3. /Nucleotides and nucleic acids