A pharmaceutical company is testing two novel therapeutic molecules designed to regulate cellular metabolism:
The simplified mechanisms of action for these two classes of messenger molecules are illustrated in the diagram below.
Based on its chemical properties, suggest the cellular location of the receptors for Lipophilic-9 (L-9) and explain how L-9 reaches them.
State the cellular location of the receptors for Hydro-P (HP) and explain why its location differs from that of the L-9 receptors.
Explain how Hydro-P (HP), which cannot cross the plasma membrane of a target cell, is still able to trigger a rapid change in the metabolic activity inside that cell.
