Coordination and control – the endocrine system

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Question 8
Hard

A patient is treated with mifepristone, a drug that acts as a potent competitive antagonist at glucocorticoid (cortisol) receptors in the brain and pituitary gland.

HPA Axis Diagram

Based on the pathway shown in the diagram, how will this drug affect the patient's endogenous secretion of corticotropin-releasing hormone (CRH) and adrenocorticotropic hormone (ACTH)?

Both CRH and ACTH secretion will decrease

Both CRH and ACTH secretion will increase

CRH secretion will increase, while ACTH secretion will decrease

CRH secretion will decrease, while ACTH secretion will increase

Coordination and control – the endocrine system Questions

  1. GCSE
  2. /Biology
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