Table 1 shows the concentration of oestrogen in the blood of an adult female during different phases of a 28-day menstrual cycle.
| Days in the cycle | Oestrogen concentration (pmol/L) |
|---|---|
| 1–5 | 110 |
| 6–12 | 290 |
| 13–15 | 920 |
| 16–23 | 450 |
| 24–28 | 130 |
Describe the changes in the oestrogen concentration during the 28-day cycle.