6.1 Reproduction

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Question 8
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Figure 1 shows the inheritance of sickle cell anaemia in one family.

A pedigree chart showing the inheritance of sickle cell anaemia across three generations, as described in the text.

Persons 6 and 7 in Figure 1 are expecting another child.

Determine the probability that the child will be a boy with sickle cell anaemia.

You should:

  • identify the genotypes of Person 6 and Person 7
  • draw a Punnett square diagram showing the possible offspring genotypes
  • identify the phenotype of each offspring genotype
  • calculate the final probability using the symbols:
    • HAH^AHA = normal haemoglobin allele
    • HSH^SHS = mutated haemoglobin allele
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6.1 Reproduction Questions

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