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Question 19

Coronary heart disease can lead to the build-up of fatty deposits (atheroma) inside the coronary arteries, restricting blood flow to the heart muscle cells.

Table 1 shows how the percentage occlusion (blockage) of a patient's coronary artery affects the blood flow rate to the downstream cardiac muscle.

Table 1

Coronary artery occlusion (%)Blood flow rate (cm3/min\text{cm}^3\text{/min}cm3/min)
0240
20192
5096
7044
9012
a.

Describe the trend shown in Table 1 between the coronary artery occlusion and the blood flow rate.

[1]
b.

Calculate the percentage decrease in the blood flow rate when the artery's occlusion increases from 0% to 50%. Show your working.

[2]
c.

Assuming the change in blood flow rate is linear between an occlusion of 50% and 70%, estimate the blood flow rate when the coronary artery is 60% occluded. Show your working.

[2]
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2 Organisation Questions

  1. GCSE
  2. /Biology
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