2.2 Animal tissues, organs and organ systems

Question 1

Hard

A clinical study compared two methods of treating a severely leaking mitral heart valve in elderly patients:

Surgical Mitral Valve Repair (SMVR) (traditional open-heart surgery)
Percutaneous Mitral Valve Repair (PMVR) (a minimally invasive catheter-based procedure)

The data from the study is shown in the table below:

Measurement	SMVR	PMVR
Number of patients in the study	$4500$	$3200$
Number of patients experiencing severe post-operative infection within 30 days	$270$	$48$
Percentage of patients alive after 5 years	$82%82\%$	$76%76\%$
Percentage of patients requiring a secondary re-intervention within 2 years	$3.5%3.5\%$	$14.0%14.0\%$

Explain how a severely leaking mitral valve leads to a reduced ability to perform aerobic exercise.

[4]

Give one conclusion comparing the rate of severe post-operative infection within 30 days between the two groups. Include calculations of percentages to support your conclusion.

[3]

Based on the data provided and your biological knowledge, evaluate the choice of PMVR compared to SMVR.

[4]

2.2 Animal tissues, organs and organ systems

Question 1

2.2 Animal tissues, organs and organ systems Questions

2.2 Animal tissues, organs and organ systems

Question 1

2.2 Animal tissues, organs and organ systems Questions