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Radionuclide imaging and therapy (A-level only)

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Question 2

X-ray photons are used in radiotherapy to target cancerous cells deep within a patient. However, a significant fraction of these photons is attenuated by healthy intervening tissues before reaching the targeted site. High-energy X-ray machines produce a spectrum of photon energies.

a.

Table 1 shows the linear attenuation coefficients of soft liver tissue for X-ray photons at energies of 250 keV250\text{ keV}250 keV and 600 keV600\text{ keV}600 keV.

Table 1

Energy / keV\text{keV}keVLinear attenuation coefficient of soft liver tissue / cm−1\text{cm}^{-1}cm−1
2500.14
6000.082

Deduce whether photons of energy 250 keV250\text{ keV}250 keV or 600 keV600\text{ keV}600 keV are more suitable for treating a localized liver tumor located at a depth of 11.0 cm. Support your answer with a calculation.

[3]
b.

Metal filters are positioned in the path of the X-ray beam to minimize dose absorption by healthy superficial tissues. Table 2 provides linear attenuation coefficient data for two potential filter materials: Aluminium and Copper.

Table 2

Energy / keV\text{keV}keVLinear attenuation coefficient of Aluminium / cm−1\text{cm}^{-1}cm−1Linear attenuation coefficient of Copper / cm−1\text{cm}^{-1}cm−1
2500.321.15
6000.210.65

Using the information provided, discuss whether Aluminium or Copper would be the superior choice of filter for the therapeutic scenario described in part (a). No calculations are required.

[3]
c.

State and explain one other method employed during external beam radiotherapy to limit radiation exposure to healthy surrounding tissues.

[2]

Radionuclide imaging and therapy (A-level only) Questions

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  3. /Radionuclide imaging and therapy (A-level only)