A pharmacist is studying the elimination of a medication from the bloodstream. The mass of the medication in the body is modeled by the equation
m=m0e−kt m = m_0 e^{-kt} m=m0e−ktwhere m0m_0m0 mg is the initial mass administered and mmm mg is the mass in the body after ttt hours.
On average, the biological half-life of this medication is 4.5 hours.
A patient is given a single dose of 300 mg of the medication.
The patient takes the 300 mg dose at 9 am. Use the model to estimate the mass of the medication remaining in the body at 3 pm.
The patient is instructed to ensure that the total mass of the medication in their body does not exceed 350 mg. The patient intends to take a second 300 mg dose. Using the model, find the earliest time they can take this second dose. Give your answer to the nearest minute.
State one reason why the mass of medication predicted by this model might not be accurate for an individual patient.
Practise Edexcel A Level Maths Integration with exam-style questions for A Level Maths. 437 questions covering 11.1 Integrating Standard Functions, 11.2 Integrating f(ax + b), 11.3 Using Trigonometric Identities, 11.4 Reverse Chain Rule, 11.5 Integration by Substitution, 11.6 Integration by Parts, 11.7 Partial Fractions, 11.8 Finding Areas, 11.9 The Trapezium Rule, 11.10 Solving Differential Equations, and 11.11 Modelling with Differential Equations, matched to the Edexcel A Level Maths (9MA0) specification and written in Paper 1, Paper 2 and Paper 3 style. Every question includes a full worked solution and mark scheme, so you can see where marks are awarded rather than just whether you got the answer right.
