Galactosemia is an inherited metabolic disorder caused by an autosomal recessive allele.
Two parents are heterozygous for galactosemia.
Describe the genetic cross of these parents. Use GGG for the dominant normal allele and ggg for the recessive galactosemia allele, identifying parental genotypes, their gametes, and the possible offspring genotypes. State the ratio of offspring without galactosemia to offspring with galactosemia.
Calculate the probability of these parents producing a male child with galactosemia.
In a certain country, the probability of a newborn being born with galactosemia is 0.000050.000050.00005. There are approximately 920,000920,000920,000 births per year in this country. Calculate the number of children born per year who are expected to have galactosemia. Show your working.