A clinical hemodialysis system functions as an artificial kidney to clear metabolic waste from patients with kidney failure.
Explain why it is biologically important that the dialysate fluid contains a glucose concentration equal to the normal blood glucose concentration of the patient.
Describe the process by which urea is cleared from the patient's bloodstream into the dialysate fluid, referencing both the mechanism and the structural properties of the hemodialysis membrane.
A synthetic hemodialysis membrane is unable to replicate the active metabolic functions of a living nephron. Describe two physiological processes that occur in a functional human nephron but do not take place in a dialysis machine. For each process, state its name and describe how it works.
When a patient receives a kidney transplant, the donor kidney must be integrated into their existing circulatory and urinary systems. Name the two major blood vessels and the anatomical duct that must be connected to the donor kidney.