Background and aim
Anterograde amnesia
An inability to form new long-term memories after an injury, illness or traumatic event, while memories from before it are usually kept.
- Wilson, Kopelman and Kapur (2008) supports the multi-store model of memory.
- The case is also evidence of the impact of neurological damage on behaviour.
- Clive Wearing, a British man born in 1938, was an outstanding musician and a gifted musical scholar.
- In 1985 he developed an influenza-type illness, later diagnosed as herpes simplex viral encephalitis, a virus which destroyed large sections of his brain.
- The aim was to record the neuropsychological assessments and experiences of an individual with a severe and rare case of both anterograde and retrograde amnesia.
- Anterograde amnesia is the inability to lay down new memories, and retrograde amnesia is the loss of memories from before the damage.
- One man could follow a conversation in the moment and score zero on the same material minutes later, which is the clearest sign that holding information now and storing it for later are separate stores.
- The virus destroyed the structures that lay down new memories and spared the ones that carry practised skills, so he could still conduct and sight-read.
- He had also lost much of his own past, so the case shows anterograde and retrograde amnesia together in one person.
Method
Case study
An in-depth investigation of a single person, group or event, usually combining several methods to gather rich, detailed data.
- The design was a longitudinal case study of one participant, producing mainly qualitative data alongside test scores.
- The sample was a single participant, Clive Wearing, first referred to Wilson in 1985 and studied on many occasions over the following 21 years.
- The materials were detailed observations, in-depth interviews, standardised tests of IQ and memory such as the Wechsler Memory Scale, and brain scans at intervals.
- His own diaries were used as evidence of how he understood what had happened to him.
- No figure is fixed for his memory span, because the study does not report one.
- His short-term memory was normal, and the long-term store is where the researchers located the damage.
Results
Long-term memory
The store that holds information over long periods, from hours to potentially a lifetime, with no known limit on how much it can hold.
- His verbal and performance IQ had declined from his pre-illness level, although both were still in the average range.
- His short-term memory was normal.
- His long-term memory was severely affected.
- He always scored zero on tests of delayed recall.
- His episodic memory was severely affected, with some semantic problems as well.
- He could not lay down new memories, and he had lost memories from before the illness, so he showed both anterograde and retrograde amnesia.
- He retained the ability to talk, read, write, conduct and sight-read music.
- In test sessions he scored zero on delayed recall, minutes after being given the material.
- In the same period he could sit down and conduct, or sight-read a score put in front of him, as fluently as before the illness.
- The recall tests and the music were drawing on different stores.
Brain scans and past awareness
- His brain differed from normal in the hippocampal formations, amygdala, mammillary bodies and temporal poles.
- Damage to the hippocampal formations fits his inability to form new long-term memories.
- His intact musical skills fit a cerebellum that the virus left undamaged.
- For years he did not accept that he had a memory disorder, explaining his difficulties by saying he had not been conscious since he became ill.
- Shown his own diaries, he agreed the handwriting was his, but said he had not been conscious when he wrote them and was conscious now for the first time.
- In 1995 Wilson et al. suggested this belief might be a delusion.
- They later concluded he was trying to make sense of why he could not remember, because he showed none of the other psychiatric features that go with delusions.
- The claim about his consciousness was the researchers' reading of what he said, and they revised it once the other features of a delusion turned out to be absent.
- Procedural memory sits inside long-term memory, so his preserved musical skill does not mean his long-term memory was unharmed.
Conclusions
Procedural memory
A type of long-term memory for how to perform learned skills and actions, such as riding a bike, which you can carry out without consciously thinking through the steps.
- His temporal lobe damage was so severe that it explains why he did not recognise the existence of his past consciousness.
- The case supports the multi-store model's claim that the stores are separate and distinct, because his two stores were affected to very different degrees.
- It also supports the idea of different types of long-term memory, since his procedural memory stayed intact while his episodic and semantic memory were damaged.
Criticisms
- Rich longitudinal data is a strength, because 21 years of assessments show the deficit was stable over time.
- Agreement between methods is a strength, because standardised tests, brain scans, observations and interviews all point the same way, which raises validity.
- An everyday setting is a strength, because the study followed memory in one man's daily life, which raises ecological validity.
- Generalisability is a weakness, because it is hard to generalise about the effects of brain damage from one person, and someone else with similar damage might be affected differently.
- The rarity of the case is a weakness, because his illness was rare and its effects were extreme, so conclusions about ordinary memory are limited.
- Subjectivity is a weakness, because some of the commentary rested on the researchers' reading of his behaviour, which mattered because he could not easily explain his own experience.
- Ethics is a weakness, because he was named rather than kept confidential, and he was tested again and again when the testing did not benefit him directly.
Turning this into marks
- Name the method as a longitudinal case study of one participant, because writing that the researchers studied a man with amnesia does not secure the knowledge mark.
- When a question asks how the case supports the multi-store model, give the results as two separate points: his normal short-term memory and his severely affected long-term memory.
- Attach each criticism to a detail of the study, such as the single participant for generalisability or the naming of the participant for ethics.
- The mark most often lost is quoting a figure for his memory span, which the study never fixes.
- State the aim of Wilson, Kopelman and Kapur (2008) and name the method.
- Which four brain areas differed from normal on his scans?
- Which memory abilities were lost, and which survived?
- Why did the researchers move from calling his belief a delusion to calling it an attempt to make sense of things?
- Explain how the case supports the multi-store model, then give one criticism of the study.