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1.2.8 Brain function, synapses and dopamine in psychoticism

Brain function and psychoticism

Definition

Synapse

The tiny gap between the end of one neuron and the start of the next, where the signal is passed from one to the other.

  1. Everything the brain does comes down to neurons passing messages to one another.
  2. The pattern of those messages produces your cognitions, meaning what you notice, want and decide.
  3. Those cognitions then drive behaviour, so a change in the chemistry between neurons can change how a person acts.
  4. The chemicals that carry a message across from one neuron to the next are neurotransmitters.
  5. Dopamine is the one that matters here, and it works in pathways that handle reward, motivation and movement.
  6. Psychoticism is the Eysenck dimension covering lack of empathy, egocentrism, aggression and anti-social behaviour.
  7. Eysenck (1992) put psychoticism down to an overactive dopamine system.
Key Idea
  • Messages cross a synapse as dopamine, and the pattern of those messages produces the cognitions that drive behaviour.
  • Eysenck (1992) put psychoticism down to an overactive dopamine system, in which dopaminergic neurons fire more often than they should.
  • That excess activity is his account of the coldness, aggression and anti-social behaviour of a high psychoticism scorer.

How a message crosses a synapse

Definition

Dopamine

A neurotransmitter involved in movement, motivation and processing information; unusual levels of activity are linked to several conditions.

  1. Neurons never touch, so every message has to cross a tiny gap called a synapse.
  2. An electrical impulse travels down the axon of the sending neuron until it reaches the end.
  3. There the impulse makes small sacs of dopamine move to the membrane and burst open.
  4. Dopamine spills into the synapse and drifts across the gap.
  5. On the far side it locks onto receptors on the receiving neuron, which only fit that one neurotransmitter.
  6. Fill enough receptors and the receiving neuron fires an impulse of its own, so the message carries on.
  7. The dopamine left in the gap is then cleared away, either taken back into the sending neuron or broken down.
  8. That clearing resets the synapse, so the next message arrives as a separate signal.
Example
  • Dopamine works like a text message sent across the gap between two neurons.
  • The receptor is the phone, and it only opens messages in one format.
  • Clearing the leftover dopamine is deleting the message so the screen is empty for the next one.

An overactive dopamine system

Definition

Dopaminergic neuron

A neuron that uses dopamine as its neurotransmitter. When it fires, it releases dopamine into the synapse so the signal can cross to the next neuron.

  1. A dopaminergic neuron is one that uses dopamine, and how often it fires is normally held down by inhibition from other neurons.
  2. Eysenck argued that in a high psychoticism scorer this inhibition is reduced.
  3. With the brake off, dopaminergic neurons fire more often than they should.
  4. Each extra firing tips more dopamine into the synapse, so more than usual sits there waiting to bind.
  5. More binding at the receptors means the receiving neuron is triggered over and over.
  6. You end up with excess dopamine activity right along the pathway, which is what an overactive dopamine system means.
Common Mistake
  • This is not the dopamine hypothesis of schizophrenia, which uses almost identical wording for a different disorder.
  • Here the outcome being explained is a personality dimension, psychoticism, not a mental health condition.
  • Dopamine does not belong to the arousal explanation of extraversion either, because that one runs through the reticular activating system and the cortex.

Dopamine and offending

  1. Dopamine pathways handle reward, so flooding them makes an immediate payoff feel unusually strong.
  2. Feel reward that strongly and you act on it fast, which is the impulsive side of psychoticism.
  3. The same over-firing is linked to aggression and to the coldness that leaves a high scorer indifferent to a victim.
  4. The evidence for the link is correlational, so high dopamine activity may sit alongside psychoticism without causing it.
  5. The strongest criticism of the theory as a whole is individual differences, because plenty of people with high psychoticism never offend and plenty of offenders score low.
Note
  • Overactive here describes how often dopaminergic neurons fire and how much dopamine sits in the synapse, rather than the total amount in the brain.
  • Dopamine activity in a living brain cannot be measured directly, so the support for this part of the theory stays indirect.
  • The same pathways handle ordinary rewards such as food, music and winning a game, so a busy dopamine system is no sign of offending by itself.

Turning this into marks

  1. Describe transmission in separate steps, from impulse to release to binding to clearing, because one summary sentence collapses several points into a single one.
  2. Name dopamine and the dopaminergic neuron, because writing that a chemical crosses the gap does not secure the knowledge mark.
  3. Say overactive and give 1992 for this part of the theory, since the claim is too much dopamine activity rather than too little.
  4. The mark most often lost is attaching dopamine to extraversion, when dopamine belongs to psychoticism and extraversion runs through arousal in the cortex.
Self review
  • What is a synapse?
  • What does a dopaminergic neuron do when it fires?
  • What happens to the dopamine left in the synapse after the signal has crossed?
  • Why does reduced inhibition produce an overactive dopamine system?
  • Which of Eysenck's three dimensions does the overactive dopamine system explain, and in which year did he propose it?
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Everything the brain does depends on neurons passing messages to one another. The pattern of these messages produces cognitions, including what a person notices, wants and decides, and cognitions then influence behaviour.

Psychoticism is Eysenck's dimension involving low empathy, egocentrism, aggression and anti-social behaviour. Eysenck (1992) explained psychoticism using an overactive dopamine system.

Dopamine is a neurotransmitter involved in reward, motivation, movement and information processing. In this theory, dopaminergic neurons fire more often than they should, producing excess dopamine activity along relevant pathways.

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What produces a person's cognitions?

1.2.8 Brain function, synapses and dopamine in psychoticism Revision Guide

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  2. /Psychology
  3. /1.2.8 Brain function, synapses and dopamine in psychoticism

Revision notes for OCR GCSE Psychology 1.2.8 Brain function, synapses and dopamine in psychoticism: explanations and worked examples.

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