Scientists want to produce a monoclonal antibody that binds to virus A but does not bind to virus B.
The antigens on the surfaces of the viruses are shown in the table.
| Virus | Antigens on the surface |
|---|---|
| A | J and K |
| B | K and L |
Three mice were each injected with one purified antigen: J, K or L. The antibodies made by lymphocytes from each mouse were tested.
| Mouse | Antibodies bind to virus A | Antibodies bind to virus B |
|---|---|---|
| 1 | Yes | No |
| 2 | Yes | Yes |
| 3 | No | Yes |
Explain which mouse's lymphocytes should be collected to produce the required monoclonal antibody. Predict which antigen the antibodies made by these lymphocytes bind to.
60 exam-style questions on AQA GCSE Biology 3.2 Monoclonal antibodies (HT only), covering 3.2.1 Producing monoclonal antibodies and 3.2.2 Uses of monoclonal antibodies. Each one has a worked solution and a mark scheme showing where the marks go.