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then mitosis separates the copied chromosomes, and finally cytokinesis divides the cytoplasm and cell membrane."},{"text":"Growth and DNA copying; cytokinesis; mitosis.","correct":false,"explanation":"This reverses the final two stages. Mitosis must separate the copied chromosomes before cytokinesis divides the cytoplasm and cell membrane into two cells."},{"text":"Mitosis; growth and DNA copying; cytokinesis.","correct":false,"explanation":"DNA must be copied before mitosis begins, otherwise each new nucleus cannot receive a complete set. The correct order is growth and DNA copying, mitosis, then cytokinesis."},{"text":"Growth and DNA copying; meiosis; cytokinesis.","correct":false,"explanation":"Meiosis produces genetically varied haploid gametes and is not a stage of this cycle. The three stages are growth and DNA copying, mitosis, and cytokinesis."}]},{"id":"1b007899-6e76-4b7e-8cc9-a9bac1558d0f","cardType":"basic","points":1,"front":"What happens to the cell during the first stage of the cell cycle?","back":"The cell grows and makes more sub-cellular structures.","mcqOptions":[{"text":"The cell grows and makes more sub-cellular structures.","correct":true,"explanation":"Before division, the cell increases in size and produces additional sub-cellular structures so that it has enough cellular material to form two daughter cells."},{"text":"The cell shrinks and breaks down its sub-cellular structures.","correct":false,"explanation":"The cell does not dismantle itself before division. It grows and makes more sub-cellular structures, providing enough cellular material for the two daughter cells."},{"text":"The cell divides and shares out its sub-cellular structures.","correct":false,"explanation":"Cell division occurs later during cytokinesis. In the first stage, the cell grows and makes more sub-cellular structures in preparation for division."},{"text":"The cell specialises and changes its sub-cellular structures.","correct":false,"explanation":"Specialisation gives a cell features suited to a function, but it is not the first cell-cycle stage. Here, the cell grows and makes more sub-cellular structures."}]},{"id":"24c41e97-cea6-4946-846e-d01c2212c429","cardType":"basic","points":1,"front":"What happens to each chromosome during the first stage?","back":"Its DNA is replicated, so each chromosome becomes two identical copies.","mcqOptions":[{"text":"Its DNA is replicated, so each chromosome becomes two identical copies.","correct":true,"explanation":"DNA replication produces two identical copies of each chromosome before mitosis, allowing one complete and genetically identical set to enter each daughter cell."},{"text":"Its DNA is halved, so each chromosome becomes one shorter copy.","correct":false,"explanation":"Chromosomal DNA is not halved before mitosis. It is replicated, producing two identical copies that can later be separated into the daughter cells."},{"text":"Its DNA is mutated, so each chromosome becomes two different copies.","correct":false,"explanation":"Replication is intended to copy DNA accurately, not deliberately mutate it. Each chromosome becomes two identical copies so the daughter cells inherit the same genetic information."},{"text":"Its DNA is separated, so each chromosome becomes two non-identical copies.","correct":false,"explanation":"Separation happens during mitosis, after DNA has been copied. In the first stage, DNA is replicated so each chromosome consists of two identical copies."}]},{"id":"a407e3e8-32a0-479d-818a-2d75c1450fae","cardType":"basic","points":1,"front":"What is one copy of a replicated chromosome called?","back":"A chromatid is one of the two identical copies of a replicated chromosome.","mcqOptions":[{"text":"A chromatid is one of the two identical copies of a replicated chromosome.","correct":true,"explanation":"After DNA replication, a chromosome consists of two identical sister chromatids. Each chromatid is one DNA copy that will later move into a daughter cell."},{"text":"A centromere is one of the two identical copies of a replicated chromosome.","correct":false,"explanation":"The centromere is the region joining sister chromatids, not either copy itself. One of the two identical chromosome copies is called a chromatid."},{"text":"A gamete is one of the two identical copies of a replicated chromosome.","correct":false,"explanation":"A gamete is a haploid reproductive cell, not part of a replicated chromosome. Each identical copy within the replicated chromosome is called a chromatid."},{"text":"A nucleus is one of the two identical copies of a replicated chromosome.","correct":false,"explanation":"The nucleus is the cell structure containing chromosomes, not a chromosome copy. One of the two identical copies of a replicated chromosome is a chromatid."}]},{"id":"c6d38ffe-2a66-4ab5-a329-620daf97736b","cardType":"basic","points":1,"front":"Why does the cell build up energy stores during the first stage?","back":"The cell builds up energy stores ready for division.","mcqOptions":[{"text":"The cell builds up energy stores ready for division.","correct":true,"explanation":"Cell division involves energy-requiring processes, including chromosome movement and production of cellular components. Building energy stores beforehand ensures that the cell is ready to divide."},{"text":"The cell builds up waste products ready for division.","correct":false,"explanation":"Waste products are removed because their accumulation can harm the cell; they do not power division. The cell instead builds up energy stores ready for division."},{"text":"The cell builds up genetic mutations ready for division.","correct":false,"explanation":"Mutations are DNA changes and are not intentionally accumulated for mitosis. The cell builds up energy stores to supply the processes required during division."},{"text":"The cell builds up digestive enzymes ready for division.","correct":false,"explanation":"Digestive enzymes break down substances but are not the required reserve for mitosis. The cell builds up energy stores to support the energy-demanding process of division."}]},{"id":"7d747fb7-a363-4ff7-8bec-8f9fb36770d3","cardType":"basic","points":1,"front":"Where do copied chromosomes move during mitosis?","back":"The copied chromosomes line up across the middle of the cell.","mcqOptions":[{"text":"The copied chromosomes line up across the middle of the cell.","correct":true,"explanation":"Copied chromosomes align across the cell’s middle during mitosis. This positioning allows spindle fibres to separate the copies evenly towards opposite ends of the cell."},{"text":"The copied chromosomes gather together at one end of the cell.","correct":false,"explanation":"Gathering at one end would prevent equal chromosome distribution. The copied chromosomes line up across the middle so their copies can be pulled to opposite ends."},{"text":"The copied chromosomes leave through the membrane of the cell.","correct":false,"explanation":"Chromosomes remain inside the cell throughout mitosis. They line up across the middle before spindle fibres pull the chromosome copies towards opposite ends."},{"text":"The copied chromosomes spread around the cytoplasm of the cell.","correct":false,"explanation":"Chromosomes do not disperse randomly through the cytoplasm. They line up across the middle, ensuring that their copies can be separated equally during mitosis."}]},{"id":"0ab6a96d-86b6-41be-9ea8-76b17b7c1cc5","cardType":"basic","points":1,"front":"What do cell fibres do during mitosis?","back":"Cell fibres pull the two copies of each chromosome to opposite ends of the cell.","mcqOptions":[{"text":"Cell fibres pull the two copies of each chromosome to opposite ends of the cell.","correct":true,"explanation":"Spindle fibres separate the identical chromosome copies and pull them to opposite ends, ensuring that each newly forming nucleus receives one complete chromosome set."},{"text":"Cell fibres pull the two copies of each chromosome to the same end of the cell.","correct":false,"explanation":"Moving both copies to the same end would give the new cells unequal chromosome sets. Fibres pull the copies to opposite ends so each nucleus receives one copy."},{"text":"Cell fibres pull the two copies of each chromosome to the cell membrane of the cell.","correct":false,"explanation":"The fibres do not move chromosomes to the outer membrane. They pull the identical copies towards opposite ends, where new nuclei will form around complete sets."},{"text":"Cell fibres pull the two copies of each chromosome to the middle of the cell.","correct":false,"explanation":"Chromosomes initially line up in the middle, but fibres then separate their copies. The copies are pulled to opposite ends so each daughter cell receives a complete set."}]},{"id":"fb2ce13d-d1a7-403a-8e90-a00e3faba568","cardType":"basic","points":2,"front":"What happens after the chromosome copies reach opposite ends?","back":"One complete set of chromosomes gathers at each end, and a nucleus forms around each set.","mcqOptions":[{"text":"One complete set of chromosomes gathers at each end, and a nucleus forms around each set.","correct":true,"explanation":"Once chromosome copies have separated, each end contains one complete set. A nuclear membrane forms around each set, producing two genetically identical nuclei."},{"text":"One single chromosome gathers at each end, and a nucleus forms around each chromosome.","correct":false,"explanation":"Each daughter nucleus needs every chromosome, not just one. A complete set of chromosomes gathers at each end, and a nucleus forms around each set."},{"text":"One half-set of chromosomes gathers at each end, and a nucleus forms around each set.","correct":false,"explanation":"A half-set would make the daughter cells haploid, which mitosis does not do. One complete chromosome set gathers at each end and becomes enclosed by a nucleus."},{"text":"One complete set of chromosomes gathers in the middle, and a nucleus forms around both sets.","correct":false,"explanation":"This confuses the earlier alignment stage with nuclear re-formation. Complete chromosome sets gather at opposite ends, and a separate nucleus forms around each set."}]},{"id":"2887d18c-f5e9-4bb9-8632-35a261aca769","cardType":"basic","points":1,"front":"What happens during cytokinesis?","back":"The cytoplasm and cell membrane divide to form two separate cells.","mcqOptions":[{"text":"The cytoplasm and cell membrane divide to form two separate cells.","correct":true,"explanation":"Cytokinesis physically separates the cell after nuclear division. The cytoplasm divides and the cell membrane separates, producing two distinct daughter cells."},{"text":"The chromosomes and nuclear membrane divide to form two separate cells.","correct":false,"explanation":"Chromosome separation and nuclear changes belong to mitosis, not cytokinesis. During cytokinesis, the cytoplasm and cell membrane divide to create two separate cells."},{"text":"The DNA and chromosomes divide to form two separate cells.","correct":false,"explanation":"DNA is replicated before mitosis, and chromosome copies separate during mitosis. Cytokinesis specifically divides the cytoplasm and cell membrane to form two cells."},{"text":"The nucleus and chromosomes divide to form two separate cells.","correct":false,"explanation":"This describes nuclear and chromosome events associated with mitosis. Cytokinesis is the division of the cytoplasm and cell membrane, which physically separates the daughter cells."}]},{"id":"f2e640b9-d931-4c4f-b42a-989c70f05003","cardType":"basic","points":1,"front":"How do the daughter cells compare genetically with the parent cell?","back":"They are genetically identical to each other and to the parent cell.","mcqOptions":[{"text":"They are genetically identical to each other and to the parent cell.","correct":true,"explanation":"DNA is copied before mitosis and identical chromosome sets are separated equally. Consequently, both daughter cells have the same genetic information as each other and the parent."},{"text":"They are genetically different from each other and from the parent cell.","correct":false,"explanation":"Genetic variation between daughter cells is associated with meiosis, not normal mitosis. Mitosis distributes replicated chromosomes equally, producing daughter cells genetically identical to the parent."},{"text":"They are genetically identical to each other but not to the parent cell.","correct":false,"explanation":"The daughter cells receive copies of the parent cell’s chromosomes, so they also match the parent genetically. They are genetically identical to each other and the parent cell."},{"text":"They are genetically different from each other but identical to the parent cell.","correct":false,"explanation":"Two cells cannot both match the parent genetically while differing from each other. Mitosis produces daughter cells genetically identical to each other and to the parent."}]},{"id":"f86f1492-5a8d-4e58-87c3-0c3b9a0dd9da","cardType":"basic","points":1,"front":"Why are the daughter cells described as diploid?","back":"Each daughter cell is diploid, containing a full set of chromosome pairs.","mcqOptions":[{"text":"Each daughter cell is diploid, containing a full set of chromosome pairs.","correct":true,"explanation":"Mitosis preserves chromosome number, so each daughter cell receives both members of every chromosome pair. It therefore has a full diploid chromosome complement."},{"text":"Each daughter cell is haploid, containing one chromosome from each pair.","correct":false,"explanation":"Haploid cells arise through meiosis, where chromosome number is halved. Mitosis preserves both chromosomes in every pair, making each daughter cell diploid."},{"text":"Each daughter cell is tetraploid, containing four copies of every chromosome.","correct":false,"explanation":"Although DNA is temporarily copied before division, the copies separate between daughter cells. Each receives a full set of chromosome pairs and remains diploid, not tetraploid."},{"text":"Each daughter cell is monoploid, containing a single unpaired chromosome.","correct":false,"explanation":"Mitosis does not reduce the cell to one unpaired chromosome. Each daughter cell receives a full set of chromosome pairs and is therefore described as diploid."}]},{"id":"d62f4546-3ed2-46a6-bbf5-b9e34095aad0","cardType":"basic","points":1,"front":"What type of cells does mitosis produce?","back":"Mitosis produces two genetically identical diploid daughter cells.","mcqOptions":[{"text":"Mitosis produces two genetically identical diploid daughter cells.","correct":true,"explanation":"Replicated chromosomes are shared equally during mitosis, producing two daughter cells with identical genetic information and the same diploid chromosome number as the parent."},{"text":"Mitosis produces four genetically different haploid daughter cells.","correct":false,"explanation":"Four varied haploid cells are the typical outcome of meiosis. Mitosis instead produces two genetically identical diploid daughter cells for growth, repair, or asexual reproduction."},{"text":"Mitosis produces two genetically different haploid daughter cells.","correct":false,"explanation":"This wrongly combines the number of cells from mitosis with features of meiosis. Mitosis produces two genetically identical daughter cells that retain the diploid chromosome number."},{"text":"Mitosis produces four genetically identical diploid daughter cells.","correct":false,"explanation":"One mitotic division separates one parent cell into two cells, not four. The result is two genetically identical diploid daughter cells."}]},{"id":"444be1ab-cc59-4517-b2d8-54cbb31e358a","cardType":"basic","points":3,"front":"Give two reasons mitosis is important in a multicellular organism.","back":"

Growth and development
Replacement of damaged, worn-out or lost cells

","mcqOptions":[{"text":"

Growth and development
Replacement of damaged, worn-out or lost cells

","correct":true,"explanation":"Mitosis increases cell number during growth and development. It also supplies genetically identical cells to replace those lost through damage, wear, or normal cell turnover."},{"text":"

Gamete production
Variation among sexually produced offspring

","correct":false,"explanation":"Gamete production and genetic variation are functions of meiosis, not mitosis. Mitosis supports growth and development and replaces damaged, worn-out, or lost cells."},{"text":"

Digestion and absorption
Removal of metabolic waste products

","correct":false,"explanation":"Digestion, absorption, and excretion are organism processes rather than purposes of mitotic division. Mitosis enables growth and development and replaces damaged, worn-out, or lost cells."},{"text":"

Respiration and movement
Transport of oxygen around the body

","correct":false,"explanation":"Respiration releases energy, while movement and oxygen transport involve specialised tissues. Mitosis is important for growth and development and for replacing damaged, worn-out, or lost cells."}]},{"id":"d5f80516-f94b-4490-a34a-c998f26f0614","cardType":"basic","points":2,"front":"How is mitosis used in asexual reproduction?","back":"In asexual reproduction, one parent produces genetically identical offspring by mitosis.","mcqOptions":[{"text":"In asexual reproduction, one parent produces genetically identical offspring by mitosis.","correct":true,"explanation":"Asexual reproduction involves a single parent and no fusion of gametes. Mitosis copies and distributes the parent’s genetic information, producing genetically identical offspring."},{"text":"In asexual reproduction, two parents produce genetically varied offspring by mitosis.","correct":false,"explanation":"Two parents and genetically varied offspring describe sexual reproduction. In asexual reproduction, one parent uses mitosis to produce genetically identical offspring."},{"text":"In asexual reproduction, one parent produces genetically varied offspring by mitosis.","correct":false,"explanation":"Mitosis copies the parent’s chromosomes and does not normally generate the variation associated with meiosis and fertilisation. One parent therefore produces genetically identical offspring."},{"text":"In asexual reproduction, two parents produce genetically identical offspring by mitosis.","correct":false,"explanation":"Asexual reproduction requires only one parent, whereas involving two parents is sexual reproduction. One parent produces genetically identical offspring through mitosis."}]},{"id":"c3129817-3e8a-4f83-a63a-4b06bea5a441","cardType":"cloze","points":null,"front":"The first stage is the [ ] stage of the cell cycle.","back":"The first stage is the longest stage of the cell cycle.","mcqOptions":[{"text":"longest","correct":true,"explanation":"The first stage occupies most of the cell cycle because the cell must grow, increase its sub-cellular structures, replicate its DNA, and build energy stores."},{"text":"shortest","correct":false,"explanation":"Confusing rapid chromosome separation with the preparation stage reverses their relative durations. The first stage is the longest because growth, DNA replication, and preparation take substantial time."},{"text":"final","correct":false,"explanation":"Cytokinesis, not growth and DNA copying, is the final stage of the cycle. The first stage is the longest because it includes extensive growth and preparation."},{"text":"middle","correct":false,"explanation":"Mitosis occurs between the preparation stage and cytokinesis, but the blank describes duration rather than position. The first stage is the longest stage of the cell cycle."}]},{"id":"195f1cda-dcfa-41b9-a480-aba370e9a422","cardType":"cloze","points":null,"front":"During mitosis, the chromosomes are [ ], not broken.","back":"During mitosis, the chromosomes are separated, not broken.","mcqOptions":[{"text":"separated","correct":true,"explanation":"During mitosis, spindle fibres separate the two identical copies of each chromosome and move them to opposite ends, preserving the genetic information in each daughter cell."},{"text":"replicated","correct":false,"explanation":"Replication occurs during the first stage before mitosis, rather than during chromosome separation. During mitosis, the chromosome copies are separated and moved to opposite ends."},{"text":"destroyed","correct":false,"explanation":"Destroying chromosomes would remove essential genetic information from the daughter cells. During mitosis, copied chromosomes are separated intact, not broken or destroyed."},{"text":"halved","correct":false,"explanation":"Mitosis does not halve the chromosome number, which is a common confusion with meiosis. Copied chromosomes are separated so each daughter cell receives a complete diploid set."}]},{"id":"56834c32-d5d8-40c4-9043-c11fa6984bed","cardType":"cloze","points":null,"front":"Each new nucleus receives a [ ], not half of each one.","back":"Each new nucleus receives a whole copy of every chromosome, not half of each one.","mcqOptions":[{"text":"whole copy of every chromosome","correct":true,"explanation":"Mitosis produces genetically identical daughter cells, so each new nucleus receives a complete copy of every chromosome rather than only one chromosome set or part of each chromosome."},{"text":"half copy of every chromosome","correct":false,"explanation":"This confuses mitosis with the chromosome-number reduction in meiosis. Mitosis keeps the chromosome number unchanged, so the right answer is a whole copy of every chromosome."},{"text":"whole copy of one chromosome","correct":false,"explanation":"A nucleus needs genetic information from every chromosome, not just one. Mitosis therefore gives each new nucleus a whole copy of every chromosome."},{"text":"two copies of every chromosome","correct":false,"explanation":"This doubles the chromosome number instead of maintaining it. During mitosis, each new nucleus receives a whole copy of every chromosome, with one copy of each chromosome."}]},{"id":"3da55d9c-aba3-4f98-86b2-e86c55a63510","cardType":"cloze","points":null,"front":"The more cells observed in a stage, the [ ] that stage takes.","back":"The more cells observed in a stage, the longer that stage takes.","mcqOptions":[{"text":"longer","correct":true,"explanation":"The proportion of cells seen in a stage estimates the proportion of the cell cycle spent in that stage. More cells in the stage therefore means it takes longer."},{"text":"shorter","correct":false,"explanation":"A smaller proportion of cells would suggest a shorter stage. A larger proportion indicates that more of the cycle is spent there, so the right answer is longer."},{"text":"faster","correct":false,"explanation":"The number of cells observed estimates duration, not the speed at which the stage happens. More cells indicate a longer stage, not a faster one."},{"text":"unchanged","correct":false,"explanation":"The observed proportion can show that stages have different durations. More cells in one stage means that stage occupies more of the cycle, so it is longer."}]},{"id":"80b0d571-a4d2-4e07-82ba-005ea0c297e9","cardType":"cloze","points":null,"front":"If 20 of 80 cells are in mitosis and the cycle takes 24 hours, mitosis lasts [ ].","back":"If 20 of 80 cells are in mitosis and the cycle takes 24 hours, mitosis lasts 6 hours.","mcqOptions":[{"text":"6 hours","correct":true,"explanation":"The fraction in mitosis is $20/80 = 1/4$. One quarter of the 24-hour cycle is $24 \\times 1/4 = 6$ hours."},{"text":"4 hours","correct":false,"explanation":"This uses 20 as a percentage rather than dividing by the total number of cells. The fraction is $20/80 = 1/4$, giving the correct duration of 6 hours."},{"text":"12 hours","correct":false,"explanation":"This treats half the cells as being in mitosis, but 20 out of 80 is one quarter. Therefore mitosis lasts $24 \\times 1/4 = 6$ hours."},{"text":"18 hours","correct":false,"explanation":"This calculates the time spent outside mitosis, since 60 of 80 cells are not in mitosis. Mitosis itself represents one quarter of 24 hours, which is 6 hours."}]}]}],"examCountdown":{"examDate":"2027-05-11","paperLabel":"Paper 1"},"heading":"1.2.2 Mitosis and the cell cycle","title":"1.2.2 Mitosis and the cell cycle Flashcards","topbar":{"backHref":"/gcse/biology/aqa/flashcards"},"topicSidebar":"$L39"}]}],"topicId":"ccbdadd6-0b02-5991-999b-5d524c652dde","walled":"$L3a"}],"$L3b","$L3c"]