Revision notes for AQA GCSE Biology Health issues. Open the guide for explanations and worked examples. Written against the AQA GCSE Biology (8461) specification, so the content matches what's examinable rather than general Biology background.
Revision notes for AQA GCSE Biology Health issues. Open the guide for explanations and worked examples. Written against the AQA GCSE Biology (8461) specification, so the content matches what's examinable rather than general Biology background.
In this topic, you need to think of health as a broad idea. Someone may not have an obvious infection, but they could still have poor mental health, poor diet, high stress, or a long-term condition affecting their wellbeing.
Health
Health is the state of physical and mental well-being.
A disease is a condition that affects the normal functioning of the body or mind. Diseases are major causes of ill health, but they are not the only causes. Diet, stress and life situations can also have a big effect on both physical and mental health.
This concept map shows how health is affected by different causes, and how diseases can interact with each other.


Big picture
Health is not just the absence of disease. It includes both physical and mental well-being, and it can be affected by disease, lifestyle and living conditions.
Some factors directly affect the body. For example, a poor diet may increase the risk of obesity, type 2 diabetes or heart disease. Other factors affect mental health. For example, long-term stress may contribute to anxiety or depression.
A person’s life situation means the circumstances they live in, such as housing, income, access to healthcare, social support and working conditions.
Linking factors to health
A student is asked to explain how stress and diet can affect health.
Diseases can be grouped into two main types.

Communicable disease
A communicable disease is a disease that can be spread between organisms. It is usually caused by a pathogen, which is a microorganism that causes disease.
Examples include measles, flu, HIV and malaria.
Non-communicable disease
A non-communicable disease is a disease that is not passed from one organism to another.
Examples include cancer, coronary heart disease, asthma and type 2 diabetes.
Assuming all diseases are infectious
Not all diseases are caused by pathogens. Cancer, asthma and heart disease are examples of non-communicable diseases, even though they can still seriously affect health.
Different types of disease can affect each other. This is important because real health problems are often connected rather than separate.
The immune system is the body’s defence system against pathogens. If it is damaged or not working properly, the person is more likely to suffer from infectious diseases.
For example, HIV can damage the immune system, making a person more likely to develop infections that their body would normally fight off.

Some viruses live inside cells. In some cases, they can damage the cell’s genetic material or affect how the cell divides. This can trigger the development of cancer.
For example, some types of HPV are linked with cervical cancer.

Sometimes, an immune reaction that originally happens because of a pathogen can later trigger allergies. An allergy is an overreaction of the immune system to a usually harmless substance.
Allergic reactions can include skin rashes and asthma symptoms.
Severe or long-term physical illness can affect mental health. For example, chronic pain, reduced independence or long hospital treatment may contribute to depression.
Disease interactions
One health problem can increase the risk of another. In exam answers, try to show the chain of cause and effect rather than just naming the diseases.
Explaining a disease interaction
A person has a disease that damages their immune system. Explain why they may become ill more often.
Scientists often study disease using data from populations.
Incidence
Incidence is the number of new cases of a disease in a population during a particular time period.
Incidence is useful because it shows how quickly new cases are appearing. It is often given as “cases per 100 000 people per year” so that different-sized populations can be compared fairly.
A useful formula is:
incidence rate=number of new cases in a time periodpopulation at risk×100 000\text{incidence rate} = \frac{\text{number of new cases in a time period}}{\text{population at risk}} \times 100\,000incidence rate=population at risknumber of new cases in a time period×100000Incidence vs total cases
Incidence means new cases in a time period. It does not mean the total number of people who already have the disease.
Calculating incidence
A town has 80 new cases of a disease in one year. The population is 40 000. Calculate the incidence per 100 000 people per year.
Disease data can be shown in different forms. You need to be able to move between numerical and graphical forms, such as from a table to a chart, or from a chart back to values.
A frequency table shows how often something occurs. For example, it might show the number of people with a disease in different age groups.
| Age group / years | Number of new cases |
|---|---|
| 0–9 | 4 |
| 10–19 | 7 |
| 20–29 | 11 |
| 30–39 | 18 |
| 40–49 | 24 |
A bar chart is used for separate categories. A histogram is used for continuous data grouped into intervals, such as age groups. A scatter diagram is used to look for a relationship between two variables.
This diagram compares the main graph types you are likely to use for disease data.


Use a bar chart when the x-axis has separate categories, such as disease type, gender, country or treatment group. The bars should have gaps between them.
Use a histogram when the x-axis is continuous data split into groups, such as age ranges. The bars touch because the intervals are continuous.
Bar chart or histogram?
If the x-axis categories are separate labels, use a bar chart. If the x-axis is a continuous scale split into groups, such as age, use a histogram.
A scatter diagram shows pairs of data for two variables. A variable is a factor that can change, such as age, number of cigarettes smoked per day, or disease incidence.

Correlation
A correlation is a relationship between two variables. In a positive correlation, one variable increases as the other increases. In a negative correlation, one variable decreases as the other increases.
Correlation is useful, but it does not automatically prove that one variable causes the other. Other factors may be involved.
Correlation does not prove causation
If a scatter diagram shows a correlation, you can say the variables are linked. You should not say one definitely causes the other unless there is enough evidence from further investigation.
Choosing and interpreting a graph
A scientist records the average number of cigarettes smoked per day and the incidence of lung cancer in several groups of people.
Epidemiology
Epidemiology is the study of patterns, causes and effects of disease in populations.
Scientists cannot usually study every single person in a population, so they use a sample.

Sample
A sample is a smaller group selected from a larger population to collect data from.
A good sample should be representative, meaning it reflects the population being studied. If a sample is not representative, the results may be misleading.
For example, if you only survey people who visit a gym, your sample may not represent the whole town’s health because gym users may have different lifestyles from non-gym users.
Good epidemiological sampling usually involves:
A bias is anything that makes data unfairly lean towards one outcome. A confounding variable is another factor that may affect the result and make it harder to identify the real cause.
Improving a disease survey
A researcher wants to find out whether asthma is more common in a town. They only ask 30 students from one school.
In the exam
Check yourself
Make a free account to read the full revision notes and worked examples.