9.5 The Quotient Rule
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A biochemist is studying the production of a specific enzyme in a bioreactor. The mass of the enzyme, MMM mg, in the reactor, ttt hours after the reaction begins, is modelled by the equation

M=1200e0.5t5+e0.5tt≥0M = \frac{1200e^{0.5t}}{5 + e^{0.5t}} \quad t \ge 0M=5+e0.5t1200e0.5t​t≥0

a.

Determine the initial mass of the enzyme in the bioreactor.

[2]
b.

According to this model, find the limiting value of the enzyme's mass as ttt becomes very large.

[2]
c.

Calculate the time elapsed since the start of the reaction when the mass of the enzyme is exactly 900 mg. Give your answer in hours and minutes to the nearest minute.

[3]
d.

Show that

dMdt=Ke0.5t(5+e0.5t)2\frac{dM}{dt} = \frac{Ke^{0.5t}}{(5 + e^{0.5t})^2}dtdM​=(5+e0.5t)2Ke0.5t​

where KKK is a constant to be determined.

[4]
e.

At time t=Tt = Tt=T, the rate of enzyme production is 40 mg/h. Find the value of TTT, giving your answer to one decimal place. (Solutions relying entirely on calculator technology are not acceptable.)

[4]

9.5 The Quotient Rule Questions

Practise Edexcel A Level Maths 9.5 The Quotient Rule with exam-style questions for A Level Maths. 29 questions, matched to the Edexcel A Level Maths (9MA0) specification and written in Paper 1, Paper 2 and Paper 3 style. Every question includes a full worked solution and mark scheme, so you can see where marks are awarded rather than just whether you got the answer right.

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9.5 The Quotient Rule Questions

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