Carboxylic acids and derivatives (A-level only)

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Question 4
Medium

Butyrophenone (1-phenylbutan-1-one) is a key intermediate in the synthesis of antipsychotic drugs and can be prepared by the electrophilic acylation of benzene with butanoyl chloride:

CH3CH2CH2COCl+C6H6→AlCl3C6H5COCH2CH2CH3+HCl \text{CH}_3\text{CH}_2\text{CH}_2\text{COCl} + \text{C}_6\text{H}_6 \xrightarrow{\text{AlCl}_3} \text{C}_6\text{H}_5\text{COCH}_2\text{CH}_2\text{CH}_3 + \text{HCl} CH3​CH2​CH2​COCl+C6​H6​AlCl3​​C6​H5​COCH2​CH2​CH3​+HCl

In a laboratory preparation, an excess of benzene is reacted with 1.33 × 10-1 kg of butanoyl chloride (Mr=106.5M_{\text{r}} = 106.5Mr​=106.5).

The percentage yield of butyrophenone is 65%.

What mass, in grams, of butyrophenone is produced?

87 g87\text{ g}87 g

120 g120\text{ g}120 g

185 g185\text{ g}185 g

285 g285\text{ g}285 g

Carboxylic acids and derivatives (A-level only) Questions

  1. A Level
  2. /Chemistry
  3. /Carboxylic acids and derivatives (A-level only)