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Patterns of inheritance

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Question 14

Phenylketonuria (PKU) is an autosomal recessive genetic disorder.

a.

Two healthy carriers of PKU have twelve children.

Calculate how many of the twelve children you would expect to:

  • have PKU
  • be carriers of PKU.
[2]
b.

A son of these parents and a female carrier of PKU have a child. Calculate the probability of the child having PKU.

[3]
c.

DNA samples can be amplified using the polymerase chain reaction (PCR). In theory, how many fragments of DNA might be present after 16 cycles of PCR?

Assume one DNA fragment was present at the beginning of the PCR process. Represent your answer in the form 10x10^x10x, where x x\,x is a log⁡10\log_{10}log10​ value rounded to two decimal places.

[4]

Patterns of inheritance Questions

  1. A Level
  2. /Biology
  3. /Patterns of inheritance