The antidiuretic hormone (ADH) receptor on the cell-surface membrane of kidney collecting duct cells is a G-protein coupled receptor (GPCR). ADH stimulates the reabsorption of water from the collecting duct.
What is the mechanism of action of ADH?
Cyclic AMP catalyses the insertion of aquaporin channels into the cell membrane.
ADH acts as a second messenger.
The ADH receptor is located in the cytoplasm of the kidney collecting duct cells.
When ADH binds to its receptor it stimulates the conversion of ATP to cyclic AMP.