Excretion as an example of homeostatic control

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Question 8
Medium

A genetic mutation in the gene encoding the vasopressin (V2\text{V}_2V2​) receptor in the cells of the collecting duct can lead to congenital nephrogenic diabetes insipidus. This mutation prevents antidiuretic hormone (ADH\text{ADH}ADH) from binding to its receptor on the cell-surface membrane of the collecting duct cells.

a.

Explain how this mutation affects the insertion of aquaporins and the subsequent permeability of the collecting duct to water.

[3]
b.

State and explain one physiological symptom a patient with this mutation would exhibit.

[2]

Excretion as an example of homeostatic control Questions

  1. A Level
  2. /Biology
  3. /Excretion as an example of homeostatic control